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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b55e5d9679ac02045de15b151f75a66cf0f492b4c3c48984b8b57fa16217f7' 
  AND token = 'ZVdUK4pAS5+1pRMY6veIozdTOB9/t6DDg0DvbLe7YQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}