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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c20d4e859048567518a78c1ed9623c6f13c07c14621a7ecc65bb15148e8014a' 
  AND token = 'BLpvL8+gsQl0K8JS1LNnTHgtdeT9ENaNv7XgfyqQOoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}