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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4ce6708a1c80ee468eb820ab9ae10e33ab5684ed0e82559aec1ac31279fe4f' 
  AND token = 'o2i/h3vWLCiZdEosetc1jYC6q8xtB2JmvyFyh97Xwd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}