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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5016212db1b6516faa813cd43188772214643a6e8ae8b950e0844e1caf7bd5' 
  AND token = 'vOG1m17WOC0v1aNXwyZJBaItofDH8MehOmW6lbn6XCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}