SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9b0196600172b8e96659731b66e181ce85c52378db0c68d21ebf32a56018002' 
  AND token = 'oB8Dm6UOozPqx1S/2Hpdo8mQWEcdNAWvGtfk4+wLyac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}