SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c57b9e089a5819e5ee52f5da5e44d85d27872304821ab840a56026bf26518e3' 
  AND token = 'oASHiR7F9x6hDEYt7xXrQmgZ+3nDrPufZ/MQLlHdmU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}