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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02b1d3b6e7db9be898df6bf8e0d2f3607dab89d83118e176ffe9388dd0349b2d' 
  AND token = 'CmMFos4jtbvZ9rg8uWBsTkNmS7abCqpNFdKrGhVrOKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}