SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5acfdf3b6d08e5897234b85caf4a1f24db014f0e123b945784817fa29fbfe2' 
  AND token = '5y0rjh8ViBBJKOzqGGdSk1KsPQuPmN17u7Q7IxmS1xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}