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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a8849f6a64159d1ec071ffd86eb00e4236a34ca82187de583475611be2b360' 
  AND token = 'MFzaG0mG9vtUT2XzJ+tBcLa6OxxFROT32h++t4Z7PsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}