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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd41c93df0313ff2f63c92dd03748b357096c2d8dc67a3aa2b658f686b4a9b3' 
  AND token = 'agaacEXUbMXP2aoBhh8oSOBNAq0rVsYxCDRzkV/gX7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}