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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818e924e4799f9578e974c30689dc8e480a8becc48679ed6c82ab94111dec87f' 
  AND token = 'SRJGZf5fOXz6mR4HOIPGmS+eJggpsGKcqwT5Zaxff/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}