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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b68432269a6b1b04b6102b98dd80fa590f1768d7f19efae8a6d38ee97cfddfe' 
  AND token = 'D9hut9NP2avmyeshCkh5TR5Dj4Lywv+rQBdwHHHBbBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}