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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a76d2087deec1f4e1251b7608883535470296a5a17f8c7091e5e6d82189f0372' 
  AND token = 'GNhC/Hl6OhDHGeN2GmWY9FHXDWCr0Y7b6Z9qYjMPXmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}