SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbe22a9d9958322d0b7fe536d242d0b5cef967919bdbb737bb7362144e9597fa' 
  AND token = 'd7HB9ql2Zwjdy56bHsn1kjhG6YEeh9BzgHTNrELU7Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}