SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2084207981cf6cc8aebe9a541db2bfc63841636c66c05e172ab8b1374b9787' 
  AND token = 'JIYINgIVvQ8RdRhMJnLHWVXTAL/1hYpmKMdCFlcOY2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}