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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eaf3a778d4395498cad7630200a1276ee087fca2b1a1fb516eec90aaa192e1f' 
  AND token = 's3REDx2OpnQLJTiHrap4CC3hb118VlHh62Mi6lk/CkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}