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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e301394fcc68e75fc84687619cb4117220494b909de99c54a0ba894f994c130e' 
  AND token = '2b6bK7rAcAUf0l+3mJS+mOiButOsVpx0ztWIrrXICGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}