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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f7f0980382234501b4fbf58332167b963c8b9b8e144bc8ab96e8b3dc8810b50' 
  AND token = 'mE5A828xIOCu2kHBSmqU8QsaMVJ8eAFWBsw7lLEBL/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}