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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6cd087306c6d3d2f6982b9b0a770216ad47e29ac053a457ec74e3641f93fa8c' 
  AND token = 'COJfj7WxU4Xbl/VPQvIU6F3upCkGlvQy8E8LedUGrME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}