SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '091a79727eef9d9844f2a3358963df0e037a4bd5cdd37ee2f62a25c7150dbe99' 
  AND token = 'duq0iC5OKNJzESYER+V+f6B3nUEF1/n/n4JXa4qPJyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}