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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5f6cf13cdbd663d4a7a2e9694a08df9722b10751bcaa8f8636b6c4fd080000' 
  AND token = 'dNz3HN4nsDH7EgRWO7dJl8z3XHfsgL945u3mAyGbanQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}