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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f78de2538d81e0d15b1d66e82cecd3502e98dfa51ec20cb0488daf21b68e3e' 
  AND token = '79Bw6owHQl0fwPpzUgQrUDVBBQO9dzY0wHO7ljEFIoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}