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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ef4127a051a9b8f890680b975fee9cdd53578330b5cff32140c0b060037f7e' 
  AND token = 'DITZHTnDeAkhIV0D1lCP9Z33Dc2iTAmC2WMaG9PP9vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}