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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca0184620ca90df6d2d79a2dc0bb1a0ccab733cb637007b0270ebd5999b66c8' 
  AND token = 'lEyqS8BE7RxTv8a77JFTMoF2+E+ErsrXp1GYq3x9CDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}