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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95bf27e7ca4dcf601e5461c14636604c9e41004a7bf21c61297e74f0d9f70bf4' 
  AND token = 'LRAL/MLeQBw8j8wWghVE4SYbSXO7HkYGRi+vGPXdh9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}