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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f391fe6ff579c546806bf23360f7e277009c009f01a76723ffed4160eff3e3a8' 
  AND token = '3KR/ZCHCPcC5biMVw3BNnj2VRC72WhImdTOs28iQoVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}