SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583b65b89edbf2939756133c242af535d978bbd59fc5ec2ed31b17ff2328ec7f' 
  AND token = 'ItUjbbd7PnMrUQb/2gKT860o0rYftCQUTLRqlaQ6WSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}