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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3066b1124187e11165daf9c90b7f1f272ca80c2b39d3e9e6271d3d342904181b' 
  AND token = 'E3qxbnkJmiIOQ3WZP97U5cU8cM/X/5kR4boAMF/5CM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}