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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '700da5c648e7a0ab4b814af9a65655ee333355a41a94b50ed928fc513d27a167' 
  AND token = '8cyitK12+Ay2xFI8kFVkQbQuVmr6S91zfapRtYJBkw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}