SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f86b357330edccee3bd7b3c3751e5135cb01dccca5ed2d88a6875759525155' 
  AND token = 'VX136qXk120R5IUKkWy9k8sSwOamxnOjqo3HO++6X2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}