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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d66826321f86f799fcf1831f463d40eb66bf95879900606dc7865e211d03f32' 
  AND token = 'glJJZK1E2zQhSzOucuH+lRk5Ixh/keVsUkeK2j56ny8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}