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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b63884eafae62b2beedc0fc6b8d3017db446877a683364aee97d1e11488fee6' 
  AND token = 'UIOpn6s4R/+peQNwWLTxhCcPEB1AXx5FlFiy26lmvx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}