SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b578fe1d3d24730a5eddd2df71020f3ae9daadef16032b0331e86f40172fc68' 
  AND token = '9ZhZAUKKgFuXZD6LTijc1iD7D8NUgCAU8R/wyTMKxVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}