SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb6f5899031819b550b5cc9180cba04fd1c2138cb2de5ac2705189608f547c8' 
  AND token = 'P1+De2x8irk4SBLeNwKKeWscIUoYjzdPpAPmWAuAt0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}