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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7301ccb9b9c8c2ff0e9d0ca07b2c7693fb95893fcdaede2571858eeebe1089ee' 
  AND token = '17ev+98KfD7sWxrOl7A8PfZJJdgphT+0e8DFPhZr2Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}