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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67f8f3c4be9e3a9e0b99e045546ff27d5f228cabbe4f12f5eb30cce1dfc15820' 
  AND token = 'uQ+22JdPf6LuUCuiR0z4dI1SwF7HHczIIcGsvvvk0Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}