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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60ffb486262a688fa49fab404fa8bc0b3c0dacf379c31b302d930da1a754f1e' 
  AND token = 'piNIY7p8nYtwgiPvkG+SlON//bH9kbvwc0G1kxFxNDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}