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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70f0d3e3a6e918d036bb76574694b5197f2e1779101a565d78da343040754762' 
  AND token = 'm/4WHzvtk4+UqkqEE2zmAjgmBc/6KABT3ZaxLCW21cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}