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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ff826278bef42c4bdb87d7ac4ade8664b5d9eb9915de74d62087b636fbd983' 
  AND token = 'gFDaOappBm3nXgekWc2Btbcdt49gBa3mCRacysf5exk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}