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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd6159d5416b9d198e705fcbe4864d7610f2c977cf90475d64a8b28356c8100' 
  AND token = 'sgWRvTpNavLc2w+JnIeUSeX7W6ayBKdb9d2I96OwOBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}