SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1e78ad9c113a0d735cba2707747a4bf59f4660e495affcf263f25382889d36' 
  AND token = '+sVFlbwkrt+W9wC0SvH8exw1DOS9Vv10SvTuoz+AcQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}