SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f55484fcabb8cb30e57e3e4302d916b96d409d315697ac8c2f3c1d3aa48907a' 
  AND token = 'MBE9/zDpCak3n60luVDIy/R6T2WSn9LKeh5NXwJbkfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}