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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd1e1041d4c59ecb0f2d191ec94787fc13f182f19b493a4a5eded5090ffd634' 
  AND token = 'snoewepK0Z4tW1oxtVvvQnJoTcMZPi27yf8qsdaKEP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}