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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c458d3616f8bf1d0c80a0a439db4eddc2d6f9a28644328e1112efc9d761a73f6' 
  AND token = 'oUNA6xQchwLHm1skBWvbUXErZfpsUs3Q3H5BzA0yMEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}