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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949f7c275db7494b0d0e21a24359c70fb375282b615967c2cf5ef8e974e13866' 
  AND token = 'zdFvOdTMrd6YrK9faPo1wJECs5tLY3yiJt8xo/BcezU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}