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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc77103a08c83fa9f7ad9cb0fb40790df185c0692b71506f66c7b0910ac9e0d' 
  AND token = 'QPMC5SIAf9RCrM7kPLNXvhCZ0JUtUjSyqdzYLRCqIpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}