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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbe71c28f944f4c6a98160a70e80fca54daa65c094be89987fde217d874272f0' 
  AND token = 'vEadUG2FkLJnRyTbLiHDgljl7unyaVzZ7EN7F89uMu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}