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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38d59ee5e64916c5d238fc2dc4187295ef78be27801b912dda51e17acd50a4a' 
  AND token = '6K7UMquGwmId5Vr0lMIe1XP5jlvVwq3Gbf5QuzMB1Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}