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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9afbdfc981e61b2275a22cbfdce28252a59ec09a2d2093c346bab9ce670be04d' 
  AND token = 'vUxT1OAx9Gx7FvyGoDhP3uqII/msTYP6vnqf2gQaSTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}