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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28052dc3bddfb1e203fa6443aba6f1399f71d7b6f15973f36b42d378e750f8d3' 
  AND token = 'X1kLb8lvsRmUe83aVAr49L9nprnNB8nYEISpyjs2eLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}